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CHEM 348: Polymer Chemistry: Reaction Searching

Intro to Reaction Searching

The reaction searching module of SciFinder is a great place to go for finding experimental protocols and related chemical transformations.

Grouping Search Results

At the top right corner of your search results, underneath the save button, you have the option to group results in a few different ways:

  • By scheme - each rx and experimental protocol in it's own tile (default)
  • By Document - multiple reactions contained in one reference will show up in the same tile
  • By transformation - lets you look at related transformations

Useful Filters

​Non-participating functional groups

  • Use this filter for identifying reactions by what remains intact

Reaction Notes

  • Filter by useful categories like Green Chemistry and Stereoselective

Getting Started

  • Make sure you have selected the "Reactions" tab in order to search in the reactions registry
  • You may search using a CAS RN obtained from a previous substance search, a PubMed ID, patent number, or substance name
  • If you use the draw tool on the end of the search bar, I would recommend searching for starting molecules before editing them.
    • Find a CAS RN by searching for a desired substance in the substance search module, and then copy/paste this number into the search bar at the top right corner of draw tool pop-up box

  • Search results will be arranged in tiles, or schemes.
  • Click on any substance in the reaction scheme to pull up a pop-up window where you can run a reference search or link to the registry of substance for more information.
    • Reagents and solvents are hyperlinked to records in the registry of substances as well
  • Click on the CAS reaction number below the reaction scheme diagram to navigate to the page on the actual reaction. Find information such as:
    • Experimental protocols and synthetic methods
    • Reaction overview including yields and steps
    • You can download synthetic methods for easy access in the lab
  • The bottom right pane in the reaction scheme tile will provide a link to more information on the publication credited for the experimental protocol. Click "Full Text" to check access at Williams or go to the DOI on the publisher's website.

Experimental Protocol v. Synthetic Methods

  • Experimental protocols are taken directly from a publication
  • Synthetic methods are rewritten from outside sources by SciFinder analysts, and allow for easy to download